MYRIOCIN

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Buy Good Quality MYRIOCIN 35891-70-4 with a minimum purity of 99% We provide high quality MYRIOCIN (CAS 35891-70-4), at a very affordable prices to our customers.

1.What is the MYRIOCIN ?

Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A. Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. It disrupts substratum adhesion of melanoma cells. It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis. Myriocin suppresses replication of the hepatitis C virus in a murine model.

Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A. Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. It disrupts substratum adhesion of melanoma cells. It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis. Myriocin suppresses replication of the hepatitis C virus in a murine model.[Cayman Chemical]

2.What is the CAS number for MYRIOCIN ?

The CAS number of MYRIOCIN is 35891-70-4.

More information of MYRIOCIN 35891-70-4 are:

CAS?Number

35891-70-4

Density

1.123 g/cm3

Melting Point

170-172℃

Boiling Point

636.7 °C at 760 mmHg

Flash Point

338.8 °C

Vapor Pressure

6.88E-19mmHg at 25°C

Refractive Index

1.521

HS CODE

29225090

PSA

141.08000

LogP

3.00930

Pka

1.79±0.50(Predicted)

3.What is the molecular formula of MYRIOCIN ?

The chemical formula of?MYRIOCIN is C21 H39 NO6 which containing 21 Carbon atoms,39 Hydrogen atoms,1 Nitrogen atoms and 6 Oxygen atoms,and the molecular weight, and the molecular weight of MYRIOCIN is 401.544

4.What is MYRIOCIN(35891-70-4)used for?

Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A. Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. It disrupts substratum adhesion of melanoma cells. It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis. Myriocin suppresses replication of the hepatitis C virus in a murine model.

InChI:InChI=1/C21H39NO6/c1-2-3-4-10-13-17(24)14-11-8-6-5-7-9-12-15-18(25)19(26)21(22,16-23)20(27)28/h9,12,18-19,23,25-26H,2-8,10-11,13-16,22H2,1H3,(H,27,28)/b12-9+/t18-,19+,21+/m0/s1

Relevant articles related to MYRIOCIN:

Article

Source

Construction of Quaternary Carbon Stereocenter of α-Tertiary Amine through Remote C-H Functionalization of Tris Derivatives: Enantioselective Total Synthesis of Myriocin

Miyagawa, Takashi,Inuki, Shinsuke,Oishi, Shinya,Ohno, Hiroaki

, p. 5485 - 5490 (2019)

5.Buy Good Quality MYRIOCIN 35891-70-4 with a minimum purity of 99%

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