Foscarnet sodium

Quality products?make an important contribution to long-term revenue and profitability. Good factory supply good Foscarnet sodium 63585-09-1

1.What is the Foscarnet sodium ?

Inhibits viral DNA polymerase and reverse transcriptase. Foscarnet is the only antiviral approved by the FDA for the treatment of acyclovir-resistant HSV infections, a growing problem in the AIDS population. Foscarnet does not require HSV-encoded thymidine kinase. Foscarnet therapy reduces the healing time, pain, and viral shedding. It is administered intravenously, 40 mg/kg every 8 to 12 hours within 7 to 10 days in patients suspected of having acyclovir-resistant herpes simplex infection. Foscarnet is administered for 10 days. Associated side effects include azotemia secondary to nephrotoxicity, hyperphosphatemia, hypocalcemia, anemia, nausea, vomiting, and genital ulceration. Patients may eventually develop resistant strains. Preliminary trials indicate that topical 1%foscarnet cream may have some benefit for the treatment of acyclovir-resistant mucocutaneous HSV infection in patients with AIDS.

: sodium 4-n-butanoyloxybenzyl phenoxycarbonylphosphonate

: 623-05-2
(4-hydroxyphenyl)methanol

: 63585-09-1,66706-14-7,111964-97-7
foscarnet

: 74270-30-7
disodium phenoxycarbonylphosphonate

Conditions

Conditions	Yield
With porcine liver carboxyesterase; at 37 ℃; Product distribution; other triesters and diesters; also in tissue (rat liver and rat intestine) homogenates; var. solvents;

: 72304-84-8
Ethyl, p-methoxyphenyl phenoxycarbonylphosphonate

: 63585-09-1,66706-14-7,111964-97-7
foscarnet

: 74270-25-0
p-Methoxyphenyl disodium oxycarbonylphosphonate

Conditions

Conditions	Yield
With sodium hydroxide; trimethylsilyl bromide; for 5h;	60%

2.What is the CAS number for Foscarnet sodium ?

The CAS number of Foscarnet sodium is 63585-09-1.

More information of Foscarnet sodium 63585-09-1 are:

CAS?Number	63585-09-1
Melting Point	62-65°C(lit.)
Boiling Point	490.7 °C at 760 mmHg
Flash Point	250.6 °C
Vapor Pressure	5.7E-11mmHg at 25°C
HS CODE	2942000000
PSA	113.13000
LogP	-0.61620

3.What are another words for Foscarnet sodium ?

Synonyms?for?Foscarnet sodium 63585-09-1:Phosphinecarboxylicacid, dihydroxy-, oxide, trisodium salt (9CI);A 29622;EHB 776;Foscavir;Gefin;Phosphonoformic acid trisodium salt;Triapten;Trisodium phosphonoformate;Foscarnet Sodium;

4.What is the molecular formula of Foscarnet sodium?

The chemical formula of ?Foscarnet sodium is?CO₅P*3Na which containing 1 Carbon atoms,5 Oxygen atoms and 1 Sodium atoms,and the molecular weight of??Foscarnet sodium?is 191.951.

5.What is Foscarnet sodium (63585-09-1) used for?

Foscamet sodium is a new, injectable antiviral agent useful in the treatment of severe cytomegalovirus retinitis in immunodepressed patients. Foscarnet sodium acts by inhibiting viral-specific DNA polymerases; its side-effects include decreased hemoglobin levels and acute tubular necrosis.

InChI:InChI=1/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3

Relevant articles related to Foscarnet sodium:

Article

Source

A NEW APPROACH TO P-C BOND FORMATION BY USING TRIMETHYLSILYL PHOSPHITES

Balszuweit, A.,Issleib, K.,Moeglein, W.,Stiebitz, B.

, p. 778 (2007/10/02)

Method for combating virus infection

, (2008/06/13)

6.Buy Foscarnet sodium with the best price .

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