4-(2-Aminoethyl)morpholine
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- Molecular Formula: C6H14N2O
- Molecular Weight: 130.19
- Appearance/Colour: clear colorless to pale yellow liq. after melting
- Vapor Pressure: 0.289mmHg at 25°C
- Melting Point: 24 °C
- Refractive Index: n20/D 1.476(lit.)
- Boiling Point: 202.6 °C at 760 mmHg
- PKA: pK1: 4.06(+2);pK2: 9.15(+1) (25°C)
- Flash Point: 76.3 °C
- PSA: 38.49000
- Density: 1.002 g/cm3
- LogP: -0.08450
4-(2-Aminoethyl)morpholine(Cas 2038-03-1) Usage
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Synthesis Reference(s) |
Journal of Medicinal Chemistry, 34, p. 1805, 1991 DOI: 10.1021/jm00110a008 |
InChI:InChI=1/C6H14N2O/c7-1-2-8-3-5-9-6-4-8/h1-7H2/p+2
2038-03-1 Relevant articles
SYNTHESIS, STRUCTURE, AND ACTION OF SOME GOSSYPOL DERIVATIVES ON THE PEROXIDATION OF THE LIPIDS OF BIOSUBSTRATES
Dalimov, D. N.,Mukhamedzhanova, E. N.,Shneivais, V. B.,Biktimirov, L.,Ismailov, A. I.,Kamaev, F. G.
, p. 603 - 607 (1989)
The synthesis has been effected of new g...
Preparation method of N-(2-aminoethyl) morpholine
-
Paragraph 0062; 0069-0072; 0073; 0080-0083, (2021/04/21)
The invention provides a preparation met...
COMPOUND INHIBITING BUTYRYLCHOLINESTERASE
-
Page/Page column 9, (2020/07/31)
The invention concerns a compound accord...
New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis
Tazarki, Helmi,Zeinyeh, Wael,Esvan, Yannick J.,Knapp, Stefan,Chatterjee, Deep,Schr?der, Martin,Joerger, Andreas C.,Khiari, Jameleddine,Josselin, Béatrice,Baratte, Blandine,Bach, Stéphane,Ruchaud, Sandrine,Anizon, Fabrice,Giraud, Francis,Moreau, Pascale
, p. 304 - 317 (2019/02/07)
Cdc2-like kinase 1 (CLK1) and dual speci...
Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer's Disease Mouse Model
Hoffmann, Matthias,Stiller, Carina,Endres, Erik,Scheiner, Matthias,Gunesch, Sandra,Sotriffer, Christoph,Maurice, Tangui,Decker, Michael
, p. 9116 - 9140 (2019/11/03)
In this study, the carbamate structure o...
2038-03-1 Process route
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5807-02-3
4-morpholinoacetonitrile
-
-
2038-03-1
4-(2-AMINOETHYL)MORPHOLINE
| Conditions | Yield |
|---|---|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 3.33333h;
|
72%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 ℃;
for 3h;
Reflux;
|
72%
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
for 3h;
Reflux;
|
72%
|
|
With
ethanol; sodium; toluene;
|
|
|
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 ℃;
for 3h;
Reflux;
|
-
-
6820-90-2
2-(2-morpholin-4-ylethyl)-1H-isoindole-1,3(2H)-dione
-
-
2038-03-1
4-(2-AMINOETHYL)MORPHOLINE
| Conditions | Yield |
|---|---|
|
With
hydrazine hydrate;
In
ethanol;
for 24h;
Reflux;
|
95%
|
|
With
hydrazine hydrate;
In
ethanol;
at 20 ℃;
Reflux;
|
95%
|
|
With
hydrogenchloride;
|
|
|
With
hydrazine hydrate;
In
ethanol;
Reflux;
|
|
|
With
hydrazine hydrate;
In
ethanol;
for 18h;
Reflux;
|
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2038-03-1 Downstream products
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106018-39-7
4-hydroxy-N-(2-morpholinoethyl)benzamide
-
116210-90-3
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-
859813-77-7
(4-methyl-6-nitro-[2]quinolyl)-(2-morpholino-ethyl)-amine
-
4476-13-5
N-[2-(4-morpholinyl)ethyl]benzamide
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