N-(2-HYDROXYPROPYL)METHACRYLAMIDE
Contact usReputable supplier selling N-(2-HYDROXYPROPYL)METHACRYLAMIDE 21442-01-3 with stock
- Molecular Formula: C7H13NO2
- Molecular Weight: 143.186
- Vapor Pressure: 2.43E-05mmHg at 25°C
- Melting Point: 67.92°C
- Refractive Index: 1.46
- Boiling Point: 321.2 °C at 760 mmHg
- PKA: 14.43±0.20(Predicted)
- Flash Point: 148.1 °C
- PSA： 49.33000
- Density: 1.002g/cm3
- LogP: 0.45040
N-(2-HYDROXYPROPYL)METHACRYLAMIDE(Cas 21442-01-3) Usage
InChI:InChI=1/C7H13NO2/c1-5(2)7(10)8-4-6(3)9/h6,9H,1,4H2,2-3H3,(H,8,10)
21442-01-3 Relevant articles
RETRACTED ARTICLE: Folic acid mediated endocytosis enhanced by modified multi stimuli nanocontainers for cancer targeting and treatment: Synthesis, characterization, in-vitro and in-vivo evaluation of therapeutic efficacy
Efthimiadou,Lelovas,Fragogeorgi,Boukos,Balafas,Loudos,Kostomitsopoulos,Theodosiou,Tziveleka,Kordas
, (2020/01/13)
Polymeric materials are in the epicenter...
COMPOSITIONS AND METHODS OF MANUFACTURING STAR POLYMERS FOR LIGAND DISPLAY AND/OR DRUG DELIVERY
-
Paragraph 00422-00424, (2020/10/28)
A star polymer of formula O[P1]-([X]-A[P...
Overcoming resistance to rituximab in relapsed non-Hodgkin lymphomas by antibody-polymer drug conjugates actively targeted by anti-CD38 daratumumab
Helman, Karel,Klener, Pavel,Mavis, Cory,Etrych, Tomá?,Janou?ková, Olga,Lidicky, Ond?ej,Machová, Daniela,Pokorná, Eva,Vo?ková, Petra
, p. 160 - 170 (2020/09/07)
B-cell non-Hodgkin lymphomas (B-NHL) rep...
Biotinylated HPMA centered polymeric nanoparticles for Bortezomib delivery
Ajazuddin,Gupta, Umesh,Nakhate, Kartik T.,Rani, Sarita,Sahoo, Rakesh K.
, (2020/03/10)
Bortezomib (BTZ) is a proteasome inhibit...
21442-01-3 Process route
-
-
78-96-6,1674-56-2
3-amino-2-propanol
-
-
920-46-7,26937-45-1
Methacryloyl chloride
-
-
21442-01-3,144865-46-3
N-(2-hydroxypropyl)methacrylamide
| Conditions | Yield |
|---|---|
|
In
dichloromethane;
at -5 - 20 ℃;
|
76%
|
|
With
sodium hydrogencarbonate;
In
dichloromethane;
at 0 - 20 ℃;
for 4h;
|
73%
|
|
With
sodium hydrogencarbonate;
In
dichloromethane;
at 0 - 20 ℃;
for 3h;
|
73%
|
|
With
sodium carbonate;
In
dichloromethane;
at 5 - 20 ℃;
|
72%
|
|
In
ethyl acetate;
at -20 - 20 ℃;
Molecular sieve;
Inert atmosphere;
|
65%
|
|
In
dichloromethane;
at 0 ℃;
|
48%
|
|
With
potassium carbonate;
In
dichloromethane;
at -10 - 20 ℃;
|
45%
|
|
With
potassium carbonate;
In
tetrahydrofuran;
at -4 - 2 ℃;
for 0.5h;
|
44%
|
|
With
2,5-bis(1,1-dimethylethyl)-1,4-benzenediol;
In
acetonitrile;
at 20 ℃;
for 0.25h;
|
38%
|
|
3-amino-2-propanol;
With
sodium hydrogencarbonate; 4-methoxy-phenol;
In
dichloromethane;
for 0.25h;
Cooling with acetone-dry ice;
Inert atmosphere;
Methacryloyl chloride;
In
dichloromethane;
at 20 ℃;
for 3.5h;
|
21.6%
|
|
In
dichloromethane;
|
|
|
With
sodium carbonate;
In
dichloromethane;
|
|
|
In
dichloromethane;
|
|
|
With
sodium carbonate;
In
dichloromethane;
|
|
|
In
dichloromethane;
|
|
|
With
triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 5h;
|
|
|
With
sodium carbonate;
In
dichloromethane;
|
|
|
With
sodium carbonate;
In
dichloromethane;
|
|
|
In
acetonitrile;
|
|
|
With
sodium hydrogencarbonate;
In
dichloromethane;
at 0 - 15 ℃;
for 1.5h;
|
|
|
3-amino-2-propanol;
With
sodium carbonate;
In
dichloromethane;
at 0 ℃;
Methacryloyl chloride;
In
dichloromethane;
at 15 ℃;
for 1h;
|
|
|
In
dichloromethane;
|
|
|
With
sodium carbonate;
In
dichloromethane;
at 20 ℃;
for 1h;
|
|
|
3-amino-2-propanol; Methacryloyl chloride;
With
sodium carbonate;
In
dichloromethane;
With
sodium sulfate;
for 1h;
|
-
-
((1-amino-2-propyl)methacrylate)methyl isobutyl ketimine
-
-
21442-01-3,144865-46-3
N-(2-hydroxypropyl)methacrylamide
| Conditions | Yield |
|---|---|
|
With
water; 4-methoxy-phenol;
In
methanol;
at 50 ℃;
for 1.5h;
|
87.1%
|
21442-01-3 Upstream products
-
78-96-6
3-amino-2-propanol
-
920-46-7
Methacryloyl chloride
-
760-93-0
methacryloyl anhydride
-
897017-30-0
(S)-2-Hydroxy-propionic acid 1-methyl-2-(2-methyl-acryloylamino)-ethyl ester
21442-01-3 Downstream products
-
288-32-4
1H-imidazole
-
1434118-32-7
N-(2-benzoyloxypropyl)methacrylamide
-
1450754-13-8
(Z)-N-[3-(2-hydroxypropylamino)-2-methyl-3-oxoprop-1-enyl]-4-nitrobenzamide
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