10-Hydroxy-2-decenoic acid

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Export Top Purity 10-Hydroxy-2-decenoic acid 14113-05-4 In Stock We provide high quality 10-Hydroxy-2-decenoic acid (CAS 14113-05-4), at a very affordable prices to our customers.

1.What is the 10-Hydroxy-2-decenoic acid ?

10-HDA is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees. 10-HDA has longevity-promoting effects in C. elegans at a concentration of 25 μM. It down-regulates matrix metalloproteinases (MMPs) in rheumatoid arthritis synovial fibroblasts at a concentration of 1.25 nM and inhibits VEGF-induced angiogenesis in HUVECs at 500 μM. 10-HDA also facilitates differentiation of neurons from neural stem/progenitor cells and promotes collagen production by skin fibroblasts at concentrations of 100 μM and 1.5 mM, respectively.

Used in Pharmaceutical Industry:
10-Hydroxy-2-decenoic acid is used as a therapeutic agent for promoting longevity, particularly in the model organism C. elegans, at a concentration of 25 μM. Its ability to down-regulate matrix metalloproteinases (MMPs) makes it a potential treatment for rheumatoid arthritis synovial fibroblasts at a concentration of 1.25 nM.
Used in Angiogenesis Inhibition:
In the field of cancer research, 10-HDA is used as an inhibitor of VEGF-induced angiogenesis in HUVECs at a concentration of 500 μM, which could have implications for the development of anti-cancer therapies.
Used in Neurological Applications:
10-Hydroxy-2-decenoic acid is used as a neurodifferentiation agent to facilitate the differentiation of neurons from neural stem/progenitor cells at a concentration of 100 μM, which may contribute to the development of treatments for neurological disorders.
Used in Dermatological Applications:
In the cosmetic and skincare industry, 10-HDA is used as a skin rejuvenation agent to promote collagen production by skin fibroblasts at a concentration of 1.5 mM, potentially leading to improved skin health and appearance.
Used in Nutritional Supplements:
Given its presence in royal jelly and its various health-promoting properties, 10-HDA can be used as an ingredient in nutritional supplements to support overall health and well-being.

2.What is the CAS number for 10-Hydroxy-2-decenoic acid ?

The CAS number of 10-Hydroxy-2-decenoic acid is 14113-05-4.

More information of 10-Hydroxy-2-decenoic acid 14113-05-4 are:

CAS?Number

14113-05-4

Density

1.038 g/cm3

Melting Point

64.0 to 68.0 °C

Boiling Point

339.2 °C at 760 mmHg

Flash Point

173.1 °C

Vapor Pressure

6.5E-06mmHg at 25°C

Refractive Index

1.465

HS CODE

29181990

PSA

57.53000

LogP

1.96010

Pka

4.78±0.10(Predicted)

3.What is the molecular formula of 10-Hydroxy-2-decenoic acid ?

The chemical formula of?10-Hydroxy-2-decenoic acid is C10H18O3 which containing 10 Carbon atoms,18 Hydrogen atoms and 3 Oxygen atoms,and the molecular weight, and the molecular weight of 10-Hydroxy-2-decenoic acid is 186.251

4.What is 10-Hydroxy-2-decenoic acid(14113-05-4)used for?

10-HDA is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees. 10-HDA has longevity-promoting effects in C. elegans at a concentration of 25 μM. It down-regulates matrix metalloproteinases (MMPs) in rheumatoid arthritis synovial fibroblasts at a concentration of 1.25 nM and inhibits VEGF-induced angiogenesis in HUVECs at 500 μM. 10-HDA also facilitates differentiation of neurons from neural stem/progenitor cells and promotes collagen production by skin fibroblasts at concentrations of 100 μM and 1.5 mM, respectively.

InChI:InChI=1/C11H22O3/c1-10(11(13)14)8-6-4-2-3-5-7-9-12/h10,12H,2-9H2,1H3,(H,13,14)

Relevant articles related to 10-Hydroxy-2-decenoic acid:

Article

Source

A new approach to the synthesis of royal jelly acid

Zong, Qian-Shou,Wu, Jian-Yi

, p. 399 - 401 (2014)

LA REACTION DE WITTIG-HORNER EN MILIEU HETEROGENE VI. SELECTIVITE DE LA REACTION SUR DES COMPOSES BIFONCTIONNELS

Villieras, Jean,Rambaud, Monique,Graff, Micheline

, p. 53 - 56 (1985)

5.Export Top Purity 10-Hydroxy-2-decenoic acid 14113-05-4 In Stock

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