(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine

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What is the (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine ?

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine is white to light yellow crystal powder, while it's Molecular Formula is C13H18FNO. An intermediate in the synthesis of Paroxetine (P205750), a selective serotonin reuptake inhibitor.

What is the CAS number for (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine ?

The CAS number of (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine is 105812-81-5.

More information of (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine 105812-81-5 are:

Synonyms

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine;Paroxol;[(3S,4R)-4-(4-Fluorophenyl)-1-methylpiperidin-3-yl]methanol;trans-(4R,3S)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine;(-)trans-4-(4-fluorophenyl)-3-hydroxymethyl-1-methyl piperidine ( Paroxetine );3-Piperidinemethanol,4-(4-fluorophenyl)-1-methyl-, (3S-trans)-;(-)-trans-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine;(-)-trans-4-(4'-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine;

CAS?Number

105812-81-5

Molecular Formula

C13H18FNO

Molecular Weight

223.29

Density

1.092 g/cm3

Melting Point

97-101 ºC

Boiling Point

300.3 ºC at 760 mmHg

Flash Point

135.4 ºC

HS CODE

29333999

PSA

23.47000

LogP

1.79120

Pka

14.93±0.10(Predicted)

What is (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine (105812-81-5) used for?

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine is a white to light yellow crystalline compound that serves as an intermediate in the synthesis of Paroxetine, a selective serotonin reuptake inhibitor (SSRI). It plays a crucial role in the pharmaceutical industry due to its involvement in the production of an essential medication for treating various mental health disorders.

InChI:InChI=1/C13H18FNO/c1-15-7-6-13(11(8-15)9-16)10-2-4-12(14)5-3-10/h2-5,11,13,16H,6-9H2,1H3/t11-,13-/m0/s1

Articles related to (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine:

Article

Source

An efficient and stereoselective synthesis of (3S,4R)-(-)-trans-4- (4′-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine

Somaiah, Sripathi,Sashikanth, Suthrapu,Raju, Veeramalla,Reddy, Karnati Venugopal

, p. 1 - 3 (2011)

Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties

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Page/Page column 35, (2010/11/27)

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