(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
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What is the (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine ?
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine is white to light yellow crystal powder, while it's Molecular Formula is C13H18FNO. An intermediate in the synthesis of Paroxetine (P205750), a selective serotonin reuptake inhibitor.
What is the CAS number for (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine ?
The CAS number of (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine is 105812-81-5.
More information of (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine 105812-81-5 are:
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Synonyms |
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine;Paroxol;[(3S,4R)-4-(4-Fluorophenyl)-1-methylpiperidin-3-yl]methanol;trans-(4R,3S)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine;(-)trans-4-(4-fluorophenyl)-3-hydroxymethyl-1-methyl piperidine ( Paroxetine );3-Piperidinemethanol,4-(4-fluorophenyl)-1-methyl-, (3S-trans)-;(-)-trans-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine;(-)-trans-4-(4'-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine; |
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CAS?Number |
105812-81-5 |
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Molecular Formula |
C13H18FNO |
|
Molecular Weight |
223.29 |
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Density |
1.092 g/cm3 |
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Melting Point |
97-101 ºC |
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Boiling Point |
300.3 ºC at 760 mmHg |
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Flash Point |
135.4 ºC |
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HS CODE |
29333999 |
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PSA |
23.47000 |
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LogP |
1.79120 |
|
Pka |
14.93±0.10(Predicted) |
What is (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine (105812-81-5) used for?
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine is a white to light yellow crystalline compound that serves as an intermediate in the synthesis of Paroxetine, a selective serotonin reuptake inhibitor (SSRI). It plays a crucial role in the pharmaceutical industry due to its involvement in the production of an essential medication for treating various mental health disorders.
InChI:InChI=1/C13H18FNO/c1-15-7-6-13(11(8-15)9-16)10-2-4-12(14)5-3-10/h2-5,11,13,16H,6-9H2,1H3/t11-,13-/m0/s1
Articles related to (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine:
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Article |
Source |
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An efficient and stereoselective synthesis of (3S,4R)-(-)-trans-4- (4′-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine |
Somaiah, Sripathi,Sashikanth, Suthrapu,Raju, Veeramalla,Reddy, Karnati Venugopal , p. 1 - 3 (2011) |
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Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties |
- Page/Page column 35, (2010/11/27) |
How to get the best price on (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine?
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